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KMID : 0857020100250010114
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Kosin Medical Journal
2010 Volume.25 No. 1 p.114 ~ p.116
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Acute Gouty Arthritis after Tissue Plasminogen Activator Therapy in a Patient with Acute Cerebral Infarction
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Kim Meyung-Kug
Yoo Bong-Goo
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Abstract
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The risk factors of gout are hyperuricemia, purine-rich diet, alcohol consumption, metabolic syndrome, use of diuretics, low-dose aspirin, and renal insufficiency. There is no report for acute gouty arthritis after using the tissue plasminogen activator (tPA). A 78-year-old woman visited emergency room due to sudden onset of dysarthria and left hemiparesis. The patient was treated with intravenous thrombolysis with tPA. After 2 days, she complained pain on both feet. In physical examination, the feet observed reddish swelling and tenderness with local heating sense of the right medial side of first metatarsophalangeal (MTP) joint area. The X-ray of both feet showed multiple small radiodense lesions of the first MTP joint. After administration of oral colchicine and analgesics, her symptoms were subsided. We report a case of acute gouty arthritis after tPA therapy for acute cerebral infarction.
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KEYWORD
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Gouty arthritis, Tissue plasminogen activator, Cerebral infarction
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